Cytokine concentrations in the cerebrospinal fluid of Great Danes with cervical spondylomyelopathy. Journal of Veterinary Internal Medicine (2014)

Martin-Vaquero P, da Costa RC, Moore SA, Gross AC, Eubank TD. Cytokine concentrations in the cerebrospinal fluid of Great Danes with cervical spondylomyelopathy. Journal of Veterinary Internal Medicine. v. 28, n.4, 1268-74, 2014.

Informações do Resumo

Disponível em: Inglês.
Total de Páginas: 8.

Prévia
Chronic inflammation is involved in the pathogenesis of human cervical spondylotic myelopathy andcould also play a role in cervical spondylomyelopathy (CSM) in dogs.
Hypothesis/Objectives: That cerebrospinal fluid (CSF) cytokine concentrations would differ between clinically normal(control) and CSM-affected Great Danes (GDs), with affected GDs showing higher levels of inflammatory cytokines, suchas interleukin (IL)-6 and monocyte chemoattractant protein-1/chemokine ligand 2 (MCP-1/CCL2).
Animals: Client-owned GDs: 15 control, 15 CSM-affected

Depoimentos